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Interactions between autologous T cell clones.

Abstract:

A human CD4 clone (Mx9/9) using the V beta 8 receptor was used as antigen to generate autologous clones (termed anti-Mx9/9 clones) which proliferate in response to this clone, but not other autologous clones. This was used as an experimental model to explore the specific interactions between autologous T cells. Anti-HLA-DR monoclonal antibodies inhibited the response of the anti-Mx9/9 clones, suggesting that these clones recognize their target antigen in association with HLA-DR. Because of th...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Cellular immunology
Volume:
128
Issue:
2
Pages:
490-502
Publication date:
1990-07-05
DOI:
EISSN:
1090-2163
ISSN:
0008-8749
URN:
uuid:dc0aaa55-f486-412d-8e84-e3659573a1a0
Source identifiers:
481750
Local pid:
pubs:481750

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