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The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella.

Abstract:

Eimeria spp. are a highly successful group of intracellular protozoan parasites that develop within intestinal epithelial cells of poultry, causing coccidiosis. As a result of resistance against anticoccidial drugs and the expense of manufacturing live vaccines, it is necessary to understand the relationship between Eimeria and its host more deeply, with a view to developing recombinant vaccines. Eimeria possesses a family of microneme lectins (MICs) that contain microneme adhesive repeat reg...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1002296

Authors


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Biotechnology and Biological Sciences Research Council More from this funder
Medical Research Council More from this funder
Wellcome Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Pathogens Journal website
Volume:
7
Issue:
10
Pages:
e1002296
Publication date:
2011-10-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:dbd89655-06dd-4608-a92d-9ba0816d24e3
Source identifiers:
206249
Local pid:
pubs:206249

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