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Patterns in haemoglobin levels over 10 years to predict diagnosis of colorectal cancer by Duke’s staging: preliminary findings using UK primary care routine blood test data

Abstract:
Stage at diagnosis of colorectal cancer influences 5-year survival: 94% at the earliest stage, but 7% at the latest. Tumour growth causes subtle changes in levels of blood components, such as haemoglobin, which may go unnoticed. Such changes have not been explored. We report patterns in haemoglobin levels up to 10 years before a diagnosis of colorectal cancer, by Duke’s tumour staging.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/s41416-018-0299-z

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; CSM
ORCID:
0000-0002-3006-8730
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health, Cancer Epidemiology Unit
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; CSM
National Institute for Health Research More from this funder
Publisher:
Nature Publisher's website
Volume:
119
Pages:
1–49
Publication date:
2018-11-08
Acceptance date:
2018-06-25
DOI:
Pubs id:
pubs:859282
URN:
uri:dbc2ad96-c1a4-4c94-b277-8ada84e8e81c
UUID:
uuid:dbc2ad96-c1a4-4c94-b277-8ada84e8e81c
Local pid:
pubs:859282

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