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Journal article

Photo-patterning of DNA oligonucleotides on silicon surfaces with micron-scale dimensions

Abstract:

A method is presented for the covalent attachment of oligonucleotides to silicon (100) surfaces patterned with micron-scale features. UV light exposure of hydrogen-terminated silicon (100) coated with alkenes functionalized with N-hydroxysuccinimide ester groups results in Si-C bonded monolayers. The N-hydroxysuccinimide ester surfaces act as a template for the subsequent covalent attachment of DNA oligonucleotides. In order to create patterns of surface attached DNA oligonucleotides with hig...

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Publication status:
Published

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Publisher copy:
10.1117/12.545736

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
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Journal:
BIOPHOTONICS NEW FRONTIER: FROM GENOME TO PROTEOME
Volume:
5461
Issue:
32
Pages:
1-8
Publication date:
2004
DOI:
ISSN:
0277-786X
URN:
uuid:dbad4845-e3b1-43ed-b5ad-67f5d9a65901
Source identifiers:
400210
Local pid:
pubs:400210

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