Journal article

Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin (HEAT): a randomised placebo-controlled trial in primary care

Abstract:: Background
Peptic ulcers in patients receiving aspirin are associated with Helicobacter pylori infection. We aimed to investigate whether H pylori eradication would protect against aspirin-associated ulcer bleeding.
Methods
We conducted a randomised, double-blind, placebo-controlled trial (Helicobacter Eradication Aspirin Trial [HEAT]) at 1208 primary care centres in the UK, using routinely collected clinical data. Eligible patients were aged 60 ... Expand abstract
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Hawkey, C., Avery, A., Coupland, C. A. C., & Hobbs, F. (2022). Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin (HEAT): a randomised placebo-controlled trial in primary care. Lancet, 400(10363), P1597–1606.

MLA Style

Hawkey, C., et al. “Helicobacter Pylori Eradication for Primary Prevention of Peptic Ulcer Bleeding in Older Patients Prescribed Aspirin (HEAT): a Randomised Placebo-Controlled Trial in Primary Care.” Lancet, vol. 400, no. 10363, Elsevier, 2022, pp. P1597–1606.

Chicago Style

Hawkey, C, A Avery, CAC Coupland, and F Hobbs. 2022. “Helicobacter Pylori Eradication for Primary Prevention of Peptic Ulcer Bleeding in Older Patients Prescribed Aspirin (HEAT): a Randomised Placebo-Controlled Trial in Primary Care.” Lancet 400 (10363): P1597–1606.
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Files:: Hawkey_et_al_2022_Helicobacter_pylori_eradicationV.pdf

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Publisher copy:: 10.1016/S0140-6736(22)01843-8

Authors

+ Hawkey, C More by this author

Role:: Author

+ Avery, A More by this author

Role:: Author

+ Coupland, CAC More by this author

Role:: Author

+ Hobbs, F More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Primary Care Health Sciences
Oxford college:: Harris Manchester College
Role:: Author
ORCID:: 0000-0001-7976-7172

+ Oxford Biomedical Research Centre More from this funder

Grant:: N/A

Publisher:: Elsevier
Journal:: Lancet More from this journal
Volume:: 400
Issue:: 10363
Pages:: P1597-1606
Publication date:: 2022-11-05
Acceptance date:: 2022-09-20
DOI:: 10.1016/S0140-6736(22)01843-8
EISSN:: 1474-547X
ISSN:: 0140-6736

Language:: English
Keywords:: FFR
Pubs id:: 1279353
Local pid:: pubs:1279353
Deposit date:: 2022-09-21

Terms of use

Copyright holder:: Hawkey et al
Copyright date:: 2022
Rights statement:: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

Licence:: CC Attribution (CC BY)

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