Journal article icon

Journal article

Effects of stimulation of the subthalamic area on oscillatory pallidal activity in Parkinson's disease.

Abstract:

The pattern of neuronal discharge within the basal ganglia is disturbed in Parkinson's disease (PD). In particular, there is a tendency for neuronal elements to synchronise at around 20 Hz in the absence of dopaminergic treatment, whereas this activity can be replaced by spontaneous synchronisation at much higher frequencies (>70 Hz) following dopaminergic treatment [J. Neurosci. 21 (2001) 1033; Brain 126 (2003) 2153]. In two PD patients (3 sides), we show that stimulating the subthalamic ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Role:
Author
Expand authors...
Journal:
Experimental neurology
Volume:
188
Issue:
2
Pages:
480-490
Publication date:
2004-08-05
DOI:
EISSN:
1090-2430
ISSN:
0014-4886
URN:
uuid:db8eb753-79d5-47da-8e14-1c10ebf3809e
Source identifiers:
70872
Local pid:
pubs:70872

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP