Spatially varying equilibria of mechanical models: application to dermal wound contraction.

Journal article

Mechanochemical models based on the Oster-Murray continuum framework have been applied to a variety of biological settings to obtain an understanding of the morphogenesis of living tissues. Wound-healing in mammalian skin is an important example, because a complex sequence of biochemical and biomechanical responses are orchestrated to close a wound by a combination of new tissue formation and wound contraction. Mechanical interactions between dermal fibroblastic cells and the collagen-rich ex...

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Authors: Olsen, L; Maini, P; Sherratt, J

• Publication status: Published
• Journal: Mathematical biosciences
• Volume: 147
• Issue: 1
• Pages: 113-129
• Publication date: 1998-01-01
• DOI: 10.1016/s0025-5564(97)00075-8
• EISSN: 1879-3134
• ISSN: 0025-5564
• Language: English
• Keywords: Biomechanics; Fibroblasts; Skin; Wound Healing; Animals; Extracellular Matrix; Collagen; Cell Movement; Humans; Mathematics; Models, Biological