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The impact of cell crowding and active cell movement on vascular tumour growth

Abstract:

A multiscale model for vascular tumour growth is presented which includes systems of ordinary differential equations for the cell cycle and regulation of apoptosis in individual cells, coupled to partial differential equations for the spatio-temporal dynamics of nutrient and key signalling chemicals. Furthermore, these subcellular and tissue layers are incorporated into a cellular automaton framework for cancerous and normal tissue with an embedded vascular network. The model is the extensi...

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Publication date:
2006-12-05
URN:
uuid:db80544f-eab5-4985-8495-f9fa2835097f
Local pid:
oai:eprints.maths.ox.ac.uk:314

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