Journal article
Genetic analysis of lung cancer and the germline impact on somatic mutation burden
- Abstract:
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Background
Germline genetic variation contributes to lung cancer (LC) susceptibility. Previous genome-wide association studies (GWAS) have implicated susceptibility loci involved in smoking behaviors and DNA repair genes, but further work is required to identify susceptibility variants.
Methods
To identify LC susceptibility loci, a family history-based genome-wide association by proxy (GWAx) of LC (48 843 European proxy LC patients, 195 387 contr... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 2.1MB, Terms of use)
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- Publisher copy:
- 10.1093/jnci/djac087
Authors
Funding
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Journal of the National Cancer Institute More from this journal
- Volume:
- 114
- Issue:
- 8
- Pages:
- 1159-1166
- Publication date:
- 2022-05-02
- Acceptance date:
- 2022-04-13
- DOI:
- EISSN:
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1460-2105
- ISSN:
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0027-8874
- Pmid:
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35511172
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1259120
- Local pid:
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pubs:1259120
- Deposit date:
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2023-03-22
Terms of use
- Copyright holder:
- Gabriel et al
- Copyright date:
- 2022
- Rights statement:
- © The Author(s) 2022. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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