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Interactions between D-ala-met-enkephalin, A10 dopaminergic neurones, and spontaneous behaviour in the rat.

Abstract:

We have investigated the interaction between opioid peptides and dopaminergic A10 (DA-A10) neurones in the ventral tegmental area (VTA). The behavioural consequences of VTA infusion of d-Ala-Met-enkephalinamide (DALA) were analyzed. DALA elicited a dose-dependent increase in locomotor activity measured in photocell cages and the circular corridor. Observations in the open field and in a hole box revealed that DALA-induced behavioural stimulation was characterized by enhancement of locomotion,...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Behavioural brain research
Volume:
1
Issue:
1
Pages:
3-24
Publication date:
1980-02-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:daec79fc-9f66-400e-b14f-5a94c93eb17c
Source identifiers:
20513
Local pid:
pubs:20513

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