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Journal article

MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct.

Abstract:

Investigation of the mechanisms activated by endogenous inhibitory pathways can lead to identification of novel targets for cardiovascular inflammatory pathologies. Here we exploited the potential protective role that melanocortin receptor type 3 (MC3-R) activation might play in a myocardial ischemia-reperfusion injury model. In resting conditions, mouse and rat heart extracts expressed MC3-R mRNA and protein, without changes following ischemia-reperfusion. At the cellular level heart macroph...

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Publication status:
Published

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Publisher copy:
10.1189/jlb.0306175

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
Journal of leukocyte biology
Volume:
76
Issue:
4
Pages:
845-853
Publication date:
2004-10-05
DOI:
EISSN:
1938-3673
ISSN:
0741-5400
URN:
uuid:dad1d4d6-88c4-431b-9169-43d5745c57ae
Source identifiers:
114632
Local pid:
pubs:114632

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