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Journal article

In vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaques.

Abstract:

Forty million people are estimated to be infected with HIV-1, and only a small fraction of those have access to life-prolonging antiretroviral treatment. As the epidemic grows there is an urgent need for effective therapeutic and prophylactic vaccines. Nonhuman primate models of immunodeficiency virus infection are essential for the preclinical evaluation of candidate vaccines. To interpret the results of these trials, comparative studies of the human and macaque immune responses are needed. ...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0700666104

Authors


Asquith, B More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
104
Issue:
15
Pages:
6365-6370
Publication date:
2007-04-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:dad04cd9-f490-4bde-ab98-de529ef2940d
Source identifiers:
210042
Local pid:
pubs:210042

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