Journal article
New approaches for biomarker discovery: the search for liver fibrosis markers in hepatitis C patients
- Abstract:
-
Despite many shortcomings, liver biopsy is regarded as the gold standard for assessing liver fibrosis. A less invasive and equally or more reliable approach would constitute a major advancement in the field. Proteomics can aid discovery of novel serological markers and these proteins can be measured in patient blood. A major challenge of discovering biomarkers in serum is the presence of highly abundant serum proteins, which restricts the levels of total protein loaded onto gels and limits th...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Version of record, pdf, 2.5MB)
-
- Publisher copy:
- 10.1021/pr101077c
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
Oxford Glycobiology Endowment
More from this funder
United Therapeutics Corp
More from this funder
Bibliographic Details
- Publisher:
- American Chemical Society Publisher's website
- Journal:
- Journal of proteome research Journal website
- Volume:
- 10
- Issue:
- 5
- Pages:
- 2643-2650
- Publication date:
- 2011-05-01
- DOI:
- EISSN:
-
1535-3907
- ISSN:
-
1535-3893
- Source identifiers:
-
124377
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:124377
- UUID:
-
uuid:dacf1c9e-f719-4d5c-8e03-fc8826597654
- Local pid:
- pubs:124377
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2011
- Notes:
- Copyright © 2011 American Chemical Society
- Licence:
- Other
If you are the owner of this record, you can report an update to it here: Report update to this record