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Journal article

hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer.

Abstract:

BACKGROUND: Hypoxia is an important mechanism of treatment resistance in head and neck squamous cell carcinoma (HNSCC). MicroRNAs are short noncoding RNAs that regulate multiple mRNAs and are frequently dysregulated in cancer. The authors have investigated the role of 3 microRNAs, including the hypoxia-induced hsa-miR-210, as potential markers of hypoxia or prognosis. METHODS: Three hypoxia-related microRNAs, hsa-miR-210, hsa-miR-21, and hsa-miR-10b, were measured in 46 samples from patients...

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Publication status:
Published

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Publisher copy:
10.1002/cncr.25009

Authors


Winter, SC More by this author
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Journal:
Cancer
Volume:
116
Issue:
9
Pages:
2148-2158
Publication date:
2010-05-05
DOI:
EISSN:
1097-0142
ISSN:
0008-543X
URN:
uuid:dac213d6-e22f-4067-a93c-633eb3454ae6
Source identifiers:
71842
Local pid:
pubs:71842

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