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Serum and tissue autoantibodies to colonic epithelium in ulcerative colitis.

Abstract:

Sera and colonic tissue-bound immunoglobulin extracts from patients with ulcerative colitis and disease controls were examined immunohistochemically and by killer cell cytotoxicity assay for the presence of anticolonic epithelial autoantibodies. IgG yields in the tissue extracts from patients with colitis and control subjects were similar, and the extracts were uniformly autoantibody negative. Of 41 sera from patients with inflammatory bowel disease, 'classical' anticolon antibody was present...

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Publication status:
Published

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Publisher copy:
10.1136/gut.32.2.163

Authors


Priddle, JD More by this author
Jewell, DP More by this author
Journal:
Gut
Volume:
32
Issue:
2
Pages:
163-166
Publication date:
1991-02-05
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
URN:
uuid:dab74a17-ebab-4dc8-abca-7017fccea892
Source identifiers:
135461
Local pid:
pubs:135461

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