Storage diseases: new insights into sphingolipid functions.

Journal article

Studying human diseases can help us to uncover important processes in normal cells. Cell biologists have recently focused on inherited sphingolipid-storage diseases. Eukaryotic life is characterized by internal membranes of various compositions, and sphingolipids are a small but important part of these membranes. Compositional differences between cellular membranes are maintained by sorting and sphingolipids are thought to organize this process by forming ordered domains of increased thicknes...

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Authors: Sillence, D; Platt, F

• Publication status: Published
• Journal: Trends in cell biology
• Volume: 13
• Issue: 4
• Pages: 195-203
• Publication date: 2003-04-01
• DOI: 10.1016/s0962-8924(03)00033-3
• EISSN: 1879-3088
• ISSN: 0962-8924
• Language: English
• Keywords: Humans; Intracellular Membranes; Animals; Endocytosis; Sphingolipidoses; Membrane Lipids; Protein Transport; Sphingolipids