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Primary sclerosing cholangitis: is any treatment worthwhile?

Abstract:

While many therapeutic agents have been evaluated in Primary Sclerosing Cholangitis (PSC), none have been shown in controlled trials to modify the course of disease. The bile acid ursodeoxycholic acid (UDCA) has been widely used in the treatment of PSC but its use remains controversial. It may have a role in providing chemoprotection against the development of colonic dysplasia/cancer in patients with associated inflammatory bowel disease. The exclusion of IgG4-associated cholangitis, which g...

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Publisher copy:
10.1007/s11894-011-0230-8

Authors


Journal:
Current gastroenterology reports
Volume:
14
Issue:
1
Pages:
17-24
Publication date:
2012-02-05
DOI:
EISSN:
1534-312X
ISSN:
1522-8037
URN:
uuid:da90e5e4-61a7-43a8-bc61-c85b30263f13
Source identifiers:
216085
Local pid:
pubs:216085

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