Journal article icon

Journal article

Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system.

Abstract:

Rat monoclonal antibodies were used to deplete selectively Lyt 2 (cytotoxic) and L3T4 (helper) T cell populations in vivo. These antibodies produced greater than 95% depletion of the respective T cell subset as determined by fluorescent antibody and cytofluorographic analyses. Antibody-treated mice were infected in the ear pinna with herpes simplex virus (HSV) and the induction of virus-specific T cell and antibody responses were monitored during the acute infection. Lyt 2-deficient mice prod...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1099/0022-1317-68-3-825

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Expand authors...
Journal:
Journal of general virology
Volume:
68 ( Pt 3)
Issue:
3
Pages:
825-833
Publication date:
1987-03-01
DOI:
EISSN:
1465-2099
ISSN:
0022-1317
Source identifiers:
9931

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP