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"Dark matter" worlds of unstable RNA and protein.

Abstract:

Astrophysicists use the term "dark matter" to describe the majority of the matter and/or energy in the universe that is hidden from view, and biologists now apply it to the new families of RNA they are uncovering. We review evidence for an analogous hidden world containing peptides. The critical experiments involved pulse-labeling human cells with tagged amino acids for periods as short as five seconds. Results are extraordinary in two respects: both nucleus and cytoplasm become labeled, and ...

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Publisher copy:
10.4161/nucl.29577

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Nucleus (Austin, Tex.)
Volume:
5
Issue:
4
Pages:
281-286
Publication date:
2014
DOI:
EISSN:
1949-1042
ISSN:
1949-1034
URN:
uuid:da72be25-7bb4-45dc-9fd0-e3eb46c39aab
Source identifiers:
493095
Local pid:
pubs:493095

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