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Thesis

Expression and functional studies of roundabout 4

Abstract:

Roundabout (Robo) receptors were first identified in neurons as guidance molecules, however growing evidence suggests that they also play a role in other cells. The aim of this thesis was to characterise the expression and function of a novel endothelial specific member of this family, Robo4. This study revealed that Robo4 is expressed primarily in vessels but also differentially expressed in tumour vessels. Interestingly Robo4 was primarily located within cytoplasmic vesicles coated with...

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Institution:
University of Oxford
Department:
Medical Sciences Division

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2006
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603849645
URN:
uuid:da66b7e3-617c-4fba-8d1e-d3169adc9812
Local pid:
td:603849645
Language:
English
Subjects:

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