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Journal article

Non-canonical autophagy LAPs lupus

Abstract:

Systemic lupus erythematosus (SLE) is an autoimmune disease whose central pathology is the recognition of, and reaction against, nuclear self-antigens by the immune system. This leads to type I interferon signalling, and the production of pathogenic auto-antibodies, which mediates much of the disease. The clinical consequences of the autoimmune response can be severe – common manifestations include rash, renal inflammation progressing to kidney failure, and neuropsychiatric involvement. The p...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/cdd.2016.55

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; KIR
Oxford college:
Somerville College
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
ORCID:
0000-0003-2846-7860
Publisher:
Nature Publishing Group Publisher's website
Journal:
Cell Death and Differentiation Journal website
Volume:
23
Issue:
8
Pages:
1267-1268
Publication date:
2016-06-10
DOI:
EISSN:
1476-5403
ISSN:
1350-9047
Pubs id:
pubs:628493
URN:
uri:da52aac0-c8d9-4acb-b163-7a8f131b371d
UUID:
uuid:da52aac0-c8d9-4acb-b163-7a8f131b371d
Local pid:
pubs:628493
Language:
English
Keywords:

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