Journal article icon

Journal article

Surface-induced unfolding of human lactoferrin.

Abstract:

We have determined the structural conformations of human lactoferrin adsorbed at the air/water interface by neutron reflectivity (NR) and its solution structure by small angle neutron scattering (SANS). The neutron reflectivity measurements revealed a strong structural unfolding of the molecule when adsorbed at the interface from a pH 7 phosphate buffer solution (PBS with a total ionic strength at 4.5 mM) over a wide concentration range. Two distinct regions, a top dense layer of 15-20 angstr...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/la047162j

Authors


Expand authors...
Journal:
Langmuir : the ACS journal of surfaces and colloids
Volume:
21
Issue:
8
Pages:
3354-3361
Publication date:
2005-04-05
DOI:
EISSN:
1520-5827
ISSN:
0743-7463
URN:
uuid:da351a15-12c9-459e-9815-73638c059133
Source identifiers:
121602
Local pid:
pubs:121602

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP