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Deep brain stimulation in multiple system atrophy mimicking idiopathic Parkinson's disease.

Abstract:

Deep brain stimulation (DBS) is approved for idiopathic Parkinson's disease (IPD) but has a poor evidence base in Parkinson-plus syndromes such as multiple system atrophy (MSA). We describe the clinical and neuropathological findings in a man who was initially diagnosed with IPD, in whom DBS was unsuccessful, and in whom MSA was unexpectedly diagnosed at a subsequent autopsy. This case report highlights that DBS is often unsuccessful in MSA and also demonstrates that MSA can masquerade as IPD...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1159/000368571

Authors


Thavanesan, N More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Farrell, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Medical Research Council More from this funder
Norman Collisson Foundation More from this funder
Charles Wolfson Charitable Trust More from this funder
Oxford Partnership Comprehensive Biomedical Research Centre More from this funder
Department of Health More from this funder
Publisher:
Karger Publisher's website
Journal:
Case Reports in Neurology Journal website
Volume:
6
Issue:
3
Pages:
232-237
Publication date:
2014-09-05
DOI:
EISSN:
1662-680X
URN:
uuid:da23f5f5-c79f-4e8d-9d56-cfce621bb16a
Source identifiers:
493501
Local pid:
pubs:493501

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