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A guide to super-resolution fluorescence microscopy.

Abstract:
For centuries, cell biology has been based on light microscopy and at the same time been limited by its optical resolution. However, several new technologies have been developed recently that bypass this limit. These new super-resolution technologies are either based on tailored illumination, nonlinear fluorophore responses, or the precise localization of single molecules. Overall, these new approaches have created unprecedented new possibilities to investigate the structure and function of cells.
Publication status:
Published

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Publisher copy:
10.1083/jcb.201002018

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Heintzmann, R More by this author
Leonhardt, H More by this author
Journal:
The Journal of cell biology
Volume:
190
Issue:
2
Pages:
165-175
Publication date:
2010-07-19
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
URN:
uuid:da0a9675-1021-4974-9e65-0255289a7993
Source identifiers:
310335
Local pid:
pubs:310335

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