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Journal article

Platelets kill circulating parasites of all major Plasmodium species in human malaria

Abstract:

Platelets are understood to assist host innate immune responses against infection, although direct evidence of this function in any human disease, including malaria, is unknown. Here we characterized platelet-erythrocyte interactions by microscopy and flow cytometry in malaria patients naturally infected with Plasmodium falciparum, P. vivax, P. malariae or P. knowlesi. Blood samples from 376 participants were collected from malaria-endemic areas of Papua, Indonesia, and Sabah, Malaysia. Plate...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1182/blood-2018-05-849307

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Role:
Author
ORCID:
0000-0003-1066-7960
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Funding agency for:
Price, RN
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Grant:
1037304
1045156
490037
605524
1047082
1047090
1066502
Australian Department of Foreign Affairs and Trade More from this funder
Publisher:
American Society of Hematology Publisher's website
Journal:
Blood Journal website
Volume:
132
Issue:
12
Pages:
1332-1344
Publication date:
2018-09-20
Acceptance date:
2018-06-27
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
Pubs id:
pubs:891019
URN:
uri:d9f7858d-5d02-415c-98fc-bc0961818a90
UUID:
uuid:d9f7858d-5d02-415c-98fc-bc0961818a90
Local pid:
pubs:891019
Language:
English

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