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Superinfection in malaria: Plasmodium shows its iron will

Abstract:

After the bite of a malaria-infected mosquito, the Plasmodium sporozoite infects liver cells and produces thousands of merozoites, which then infect red blood cells, causing malaria. In malaria-endemic areas, several hundred infected mosquitoes can bite an individual each year, increasing the risk of superinfection. However, in infants that are yet to acquire immunity, superinfections are infrequent. We have recently shown that blood-stage parasitaemia, above a minimum threshold, impairs the ...

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Publisher copy:
10.1038/embor.2011.213

Authors


Journal:
EMBO Reports
Volume:
12
Issue:
12
Pages:
1233-1242
Publication date:
2011-12-05
DOI:
EISSN:
1469-3178
ISSN:
1469-221X
URN:
uuid:d9ac15d1-05ca-4612-9701-008f110266d9
Source identifiers:
221614
Local pid:
pubs:221614

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