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Thesis

Mechanisms of Type 2 diabetes susceptibility

Abstract:

Type 2 diabetes (T2D) has a genetic component which is only partially understood. The majority of genetic variance in disease susceptibility is unaccounted for, whilst the precise transcripts and molecular mechanisms through which most risk variants exert their effect is unclear. A complete understanding of T2D susceptibility mechanisms could have benefits in risk prediction, and in drug discovery through the identification of novel therapeutic targets. Work presented in this thesis aims t...

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Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Research group:
Oxford Centre for Diabetes, Endocrinology and Metabolism
Oxford college:
St Hilda's College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
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Funding agency for:
Mary E Travers
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:d99892d8-534a-4908-b5dc-ab1d8b1cab52
Local pid:
ora:6887

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