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Journal article

Construction and immunogenicity in a prime-boost regimen of a Semliki Forest virus-vectored experimental HIV clade A vaccine.

Abstract:

A novel, experimental subunit human immunodeficiency virus (HIV) vaccine, SFV.HIVA, was constructed. This consists of Semliki Forest virus (SFV), which is a suitable vaccine vector for use in humans, and a passenger gene encoding HIVA, which is an immunogen derived from HIV-1 clade A that is being currently tested in clinical trials of combined DNA- and modified vaccinia virus Ankara (MVA)-vectored vaccines in Oxford (UK) and Nairobi (Kenya). In the mouse, the SFV.HIVA vaccine was highly immu...

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Publication status:
Published

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Publisher copy:
10.1099/vir.0.18738-0

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Barnfield, C More by this author
Samuel, RV More by this author
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Journal:
The Journal of general virology
Volume:
84
Issue:
Pt 2
Pages:
361-368
Publication date:
2003-02-05
DOI:
EISSN:
1465-2099
ISSN:
0022-1317
URN:
uuid:d9948b7c-3ccb-47ad-aa9e-cb9641af0d9d
Source identifiers:
66998
Local pid:
pubs:66998

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