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Long micro-channel electrode arrays: a novel type of regenerative peripheral nerve interface.

Abstract:

We have demonstrated that micro-channel electrode arrays with 100 microm x 100 microm cross-section channels support axon regeneration well, and that micro-channels of similar calibre and up to 5 mm long can support axon regeneration and vascularisation. They may be microfabricated using silicon, silicone, or polyimide and thin metal films to form 3-D bundles of long micro-channels. Arrays of "mini-nerves," i.e., miniature nerve fascicles with their own blood vessels, successfully grew throug...

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Publication status:
Published

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Publisher copy:
10.1109/tnsre.2009.2031241

Authors


Lacour, SP More by this author
Fitzgerald, JJ More by this author
McMahon, S More by this author
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Journal:
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Volume:
17
Issue:
5
Pages:
454-460
Publication date:
2009-10-05
DOI:
EISSN:
1558-0210
ISSN:
1534-4320
URN:
uuid:d991a835-2aa9-487b-ac85-ed0c4e3f211c
Source identifiers:
369584
Local pid:
pubs:369584

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