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Journal article

Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice.

Abstract:

OBJECTIVE: Susceptibility to inflammatory arthritis is determined by a complex set of environmental and genetic factors, but only a portion of the genetic effect can be explained. Conventional genome-wide screens of arthritis models using crosses between inbred mice have been hampered by the low resolution of results and by the restricted range of natural genetic variation sampled. The aim of this study was to address these limitations by performing a genome-wide screen for determinants of ar...

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Publication status:
Published

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Publisher copy:
10.1002/art.30425

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Journal:
Arthritis and rheumatism
Volume:
63
Issue:
9
Pages:
2630-2640
Publication date:
2011-09-05
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
URN:
uuid:d975d57e-95e2-4881-bbdc-7e4ead0cae36
Source identifiers:
186214
Local pid:
pubs:186214

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