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Genetic material should be routinely collected in clinical vaccine trials--high consent rates can be achieved across all age groups.

Abstract:

BACKGROUND: Genomic and transcriptomic studies underpin much investigation in biology and should be included routinely in clinical trials such as vaccine studies to provide new insight into the development of immunity and the genetic basis for adverse reactions. Interest in collecting and storing genetic material for subsequent high-throughput meta-analyses has increased substantially in recent years. Participants in clinical trials represent an important and invaluable source of clinical ma...

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Publication status:
Published

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Authors


O'Connor, D More by this author
Darton, TC More by this author
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Journal:
Vaccine
Volume:
31
Issue:
25
Pages:
2744-2748
Publication date:
2013-06-05
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
URN:
uuid:d973ef71-e663-4e89-ba89-b28d94864a3b
Source identifiers:
401987
Local pid:
pubs:401987

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