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Journal article

VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice.

Abstract:

Pulmonary metastasis is a frequent cause of poor outcome in cancer patients. The formation of pulmonary metastasis is greatly facilitated by recruitment of myeloid cells, which are crucial for tumor cell survival and extravasation. During inflammation, homing of myeloid cells is mediated by endothelial activation, raising the question of a potential role for endothelial activation in myeloid cell recruitment during pulmonary metastasis. Here, we show that metastatic tumor cell attachment caus...

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Publication status:
Published

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Journal:
Blood
Volume:
121
Issue:
16
Pages:
3289-3297
Publication date:
2013-04-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:d954da89-bcb1-48fd-bfcd-0f54a73e765f
Source identifiers:
384172
Local pid:
pubs:384172

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