Discrimination of men with prostate cancer from those with benign disease by measurements of human glandular kallikrein 2 (HK2) in serum.

Journal article

PURPOSE: To investigate the clinical value of measuring human glandular kallikrein 2 (hK2) compared with free and total prostate specific antigen (PSA-F and PSA-T) in serum from patients with prostate disease. MATERIALS AND METHODS: Serum from healthy controls, from men with benign prostate hyperplasia (BPH), clinically localized prostate cancer (PCa), and advanced PCa were analyzed for hK2 (using an in-house-research assay with detection limit of 0.05 ng./mL and <0.1% cross-reaction with ...

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Authors: Becker, C; Piironen, T; Pettersson, K; Björk, T; Wojno, K

• Publisher: Lippincott Williams and Wilkins
• Journal: Journal of urology
• Volume: 163
• Issue: 1
• Pages: 311-316
• Publication date: 2000-01-01
• DOI: 10.1097/00005392-200001000-00087
• EISSN: 1527-3792
• ISSN: 0022-5347
• Language: English
• Keywords: Tissue Kallikreins; Humans; Middle Aged; Prostatic Neoplasms; Adult; Male; Prostatic Hyperplasia; Aged, 80 and over; Prostate-Specific Antigen; Diagnosis, Differential; Aged