Journal article icon

Journal article

Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.

Abstract:

BACKGROUND: Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of action remains unclear. One possibility is that DBS suppresses local pathologically synchronised oscillatory activity. METHODS: To explore this, the authors recorded from DBS electrodes implanted in the STN of 16 patients with Parkinson's disease during simultaneous stimulation (pulse width 60 μs; frequency 130 Hz) of...

Expand abstract

Actions


Access Document


Publisher copy:
10.1136/jnnp.2010.217489

Authors


Expand authors...
Journal:
Journal of neurology, neurosurgery, and psychiatry
Volume:
82
Issue:
5
Pages:
569-573
Publication date:
2011-05-05
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
URN:
uuid:d93ab84d-dc5d-47b3-ba65-4e190b9068b7
Source identifiers:
122494
Local pid:
pubs:122494

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP