The sex-determination genes fruitless and doublesex specify a neural substrate required for courtship song.

Journal article

Courtship song is a critical component of male courtship behavior in Drosophila, making the female more receptive to copulation and communicating species-specific information [1-6]. Sex mosaic studies have shown that the sex of certain regions of the central nervous system (CNS) is critical to song production [7]. Our examination of one of these regions, the mesothoracic ganglion (Msg), revealed the coexpression of two sex-determination genes, fruitless (fru) and doublesex (dsx). Because both...

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Authors: Rideout, E; Billeter, J; Goodwin, S

• Publication status: Published
• Journal: Current biology : CB
• Volume: 17
• Issue: 17
• Pages: 1473-1478
• Publication date: 2007-09-01
• DOI: 10.1016/j.cub.2007.07.047
• EISSN: 1879-0445
• ISSN: 0960-9822
• Language: English
• Keywords: Sex Characteristics; Protein Isoforms; Drosophila; DNA-Binding Proteins; Transcription Factors; Central Nervous System; Sex Determination Processes; Ganglia, Invertebrate; Drosophila Proteins; Animals; Gene Expression; Male; Neuromuscular Junction; Nerve Tissue Proteins; Female; Sexual Behavior, Animal