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Journal article

Load-dependent effects of apelin on murine cardiomyocytes

Abstract:

The apelin peptide is described as one of the most potent inotropic agents, produced endogenously in a wide range of cells, including cardiomyocytes. Despite positive effects on cardiac contractility in multicellular preparations, as well as indications of cardio-protective actions in several diseases, its effects and mechanisms of action at the cellular level are incompletely understood. Here, we report apelin effects on dynamic mechanical characteristics of single ventricular cardiomyocytes...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.pbiomolbio.2017.09.013

Authors


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Role:
Author
ORCID:
0000-0002-5708-6410
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Role:
Author
ORCID:
0000-0002-6333-4791
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Oxford college:
University College
Role:
Author
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Funding agency for:
Bollensdorff, C
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Funding agency for:
Rog-Zielinska, EA
Publisher:
Elsevier Publisher's website
Journal:
Progress in Biophysics and Molecular Biology Journal website
Volume:
130
Issue:
Part B
Pages:
333-343
Publication date:
2017-09-18
Acceptance date:
2017-09-08
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
Pubs id:
pubs:732987
URN:
uri:d8fa7c4b-f56e-49c1-92f0-451984cc0705
UUID:
uuid:d8fa7c4b-f56e-49c1-92f0-451984cc0705
Local pid:
pubs:732987

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