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Journal article

Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.

Abstract:

Uterine leiomyomata (UL), the most prevalent pelvic tumors in women of reproductive age, pose a major public health problem given their high frequency, associated morbidities, and most common indication for hysterectomies. A genetic component to UL predisposition is supported by analyses of ethnic predisposition, twin studies, and familial aggregation. A genome-wide SNP linkage panel was genotyped and analyzed in 261 white UL-affected sister-pair families from the Finding Genes for Fibroids s...

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Publication status:
Published

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Publisher copy:
10.1016/j.ajhg.2012.08.009

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Journal:
American journal of human genetics
Volume:
91
Issue:
4
Pages:
621-628
Publication date:
2012-10-05
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:d89b85d3-829b-49ea-b6e9-c216fdaabd38
Source identifiers:
353953
Local pid:
pubs:353953

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