- Abstract:
-
Molecular classification of colorectal cancer (CRC) is currently based on microsatellite instability (MSI), KRAS or BRAF mutation and, occasionally, chromosomal instability (CIN). Whilst useful, these categories may not fully represent the underlying molecular subgroups. We screened 906 stage II/III CRCs from the VICTOR clinical trial for somatic mutations. Multivariate analyses (logistic regression, clustering, Bayesian networks) identified the primary molecular associations. Positive associ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/path.4139
-
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- Journal:
- The Journal of pathology
- Volume:
- 229
- Issue:
- 3
- Pages:
- 441-448
- Publication date:
- 2013-02-05
- DOI:
- EISSN:
-
1096-9896
- ISSN:
-
0022-3417
- URN:
-
uuid:d84215ff-b21c-426a-9888-bbb8f859012e
- Source identifiers:
-
363808
- Local pid:
- pubs:363808
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.
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