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Journal article

Psychosis: an autoimmune disease?

Abstract:

Psychotic disorders are common and disabling. Overlaps in clinical course in addition to epidemiological and genetic associations raise the possibility that autoimmune mechanisms may underlie some psychoses, potentially offering novel therapeutic approaches. Several immune loci including the major histocompatibility complex and B-cell markers CD19 and CD20 achieve genome-wide significance in schizophrenia. Emerging evidence suggests a potential role via neurodevelopment in addition to classic...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/imm.12795

Authors


Al-Diwani, AAJ More by this author
Pollak, TA More by this author
More by this author
Department:
St Hildas College
Lennox, BR More by this author
National Institute for Health Research More from this funder
UCB-Oxford Alliance More from this funder
Epilepsy Research UK More from this funder
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Publisher:
Wiley Publisher's website
Journal:
Immunology Journal website
Publication date:
2017-07-05
Acceptance date:
2017-07-05
DOI:
EISSN:
1365-2567
ISSN:
0019-2805
Pubs id:
pubs:709546
URN:
uri:d83b7d76-2247-41d3-88d7-07e9b4b11b55
UUID:
uuid:d83b7d76-2247-41d3-88d7-07e9b4b11b55
Local pid:
pubs:709546

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