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Characterization of a novel IncHI2 plasmid carrying tandem copies of blaCTX-M-2 in a fosA6-harboring Escherichia coli ST410 strain

Abstract:

Extended-spectrum β-lactamase gene blaCTX-M-2 is mainly associated with ISCR1 embedded in complex sul1-type integrons, but information on the genetic context of plasmids harboring the ISCR1-blaCTX-M-2module remains limited. In this study, a blaCTX-M-2-harboring plasmid pYD786-1 belonging to novel ST2-IncHI2 was sequenced and analyzed from an Escherichia coli ST410 clinical strain. pYD786-1 belonged to APEC-O1-R type IncHI2 plasmids which are widely distributed in human, poultry and livestock ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/AAC.01173-16

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Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
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Funding agency for:
Stoesser, N
Publisher:
American Society for Microbiology Publisher's website
Journal:
Antimicrobial Agents and Chemotherapy Journal website
Volume:
60
Issue:
11
Pages:
6742-6747
Publication date:
2016-08-29
Acceptance date:
2016-08-23
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
Pubs id:
pubs:642090
URN:
uri:d81f5089-f1d2-4084-bc2b-590d7ee6c26b
UUID:
uuid:d81f5089-f1d2-4084-bc2b-590d7ee6c26b
Local pid:
pubs:642090
Language:
English
Keywords:

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