- Abstract:
-
Allergen-specific immunoglobulin E (present in allergic sensitization) has a central role in the pathogenesis of allergic disease. We performed the first large-scale genome-wide association study (GWAS) of allergic sensitization in 5,789 affected individuals and 10,056 controls and followed up the top SNP at each of 26 loci in 6,114 affected individuals and 9,920 controls. We increased the number of susceptibility loci with genome-wide significant association with allergic sensitization from ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/ng.2694
-
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- Journal:
- Nature genetics
- Volume:
- 45
- Issue:
- 8
- Pages:
- 902-906
- Publication date:
- 2013-08-05
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:d811297d-c19a-4c9d-99e8-eb7a73023272
- Source identifiers:
-
410947
- Local pid:
- pubs:410947
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.
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