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Artesunate and mefloquine in the treatment of uncomplicated multidrug-resistant hyperparasitaemic falciparum malaria.

Abstract:

Oral artesunate is the most effective treatment for uncomplicated hyperparasitaemia in falciparum malaria. To assess the contribution of mefloquine to therapeutic efficacy in an area endemic for mefloquine-resistant Plasmodium falciparum, an open randomized comparison of a 5 d course of oral artesunate (total dose 12 mg/kg) with and without a single dose of mefloquine (25 base mg/kg) was conducted in 100 adults and children with uncomplicated hyperparasitaemia (> 4% parasitized red blood c...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Luxemburger, C More by this author
van Vugt, M More by this author
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Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
92
Issue:
2
Pages:
207-211
Publication date:
1998
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:d8071f66-083e-4b29-90bd-428e0f2c150b
Source identifiers:
23490
Local pid:
pubs:23490

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