Heterogeneity of microsatellite mutations within and between loci, and implications for human demographic histories.

Di Rienzo, A; Donnelly, P; Toomajian, C; Sisk, B; Hill, A; Petzl-Erler, ML; Haines, GK; Barch, DH

Abstract:

Microsatellites have been widely used to reconstruct human evolution. However, the efficient use of these markers relies on information regarding the process producing the observed variation. Here, we present a novel approach to the locus-by-locus characterization of this process. By analyzing somatic mutations in cancer patients, we estimated the distributions of mutation size for each of 20 loci. The same loci were then typed in three ethnically diverse population samples. The generalized s...

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APA Style

Di Rienzo, A., Donnelly, P., Toomajian, C., Sisk, B., Hill, A., Petzl-Erler, M. L., Haines, G. K., & Barch, D. H. (1998). Heterogeneity of microsatellite mutations within and between loci, and implications for human demographic histories. Genetics, 148(3), 1269–1284.

MLA Style

Di Rienzo, A., et al. “Heterogeneity of Microsatellite Mutations within and between Loci, and Implications for Human Demographic Histories.” Genetics, vol. 148, no. 3, 1998, pp. 1269–84.

Chicago Style

Di Rienzo, A, P Donnelly, C Toomajian, B Sisk, A Hill, ML Petzl-Erler, GK Haines, and DH Barch. 1998. “Heterogeneity of Microsatellite Mutations within and between Loci, and Implications for Human Demographic Histories.” Genetics 148 (3): 1269–84.
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