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Journal article

Biology of upper-body and lower-body adipose tissue-link to whole-body phenotypes.

Abstract:

The distribution of adipose tissue in the body has wide-ranging and reproducible associations with health and disease. Accumulation of adipose tissue in the upper body (abdominal obesity) is associated with the development of cardiovascular disease, insulin resistance, type 2 diabetes mellitus and even all-cause mortality. Conversely, accumulation of fat in the lower body (gluteofemoral obesity) shows opposite associations with cardiovascular disease and type 2 diabetes mellitus when adjusted...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/nrendo.2014.185

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Role:
Author
Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Reviews Endocrinology Journal website
Volume:
11
Pages:
90–100
Publication date:
2015-01-01
DOI:
EISSN:
1759-5037
ISSN:
1759-5029
URN:
uuid:d7f41e19-46a5-44b2-8993-7572d1a0fb2d
Source identifiers:
488481
Local pid:
pubs:488481
Language:
English

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