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Journal article

Female inheritance of malarial lap genes is essential for mosquito transmission.

Abstract:

Members of the LCCL/lectin adhesive-like protein (LAP) family, a family of six putative secreted proteins with predicted adhesive extracellular domains, have all been detected in the sexual and sporogonic stages of Plasmodium and have previously been predicted to play a role in parasite-mosquito interactions and/or immunomodulation. In this study we have investigated the function of PbLAP1, 2, 4, and 6. Through phenotypic analysis of Plasmodium berghei loss-of-function mutants, we have demons...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.0030030

Authors


Mendoza, J More by this author
Stanway, RR More by this author
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Wellcome Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
3
Issue:
3
Pages:
e30
Publication date:
2007-03-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:d7cc195d-6434-4927-ab3c-05b6a80265a1
Source identifiers:
260756
Local pid:
pubs:260756

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