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Journal article

Galectin-3 maintains cell motility from the subventricular zone to the olfactory bulb.

Abstract:

The adult brain subventricular zone (SVZ) produces neuroblasts that migrate through the rostral migratory stream (RMS) to the olfactory bulb (OB) in a specialized niche. Galectin-3 (Gal-3) regulates proliferation and migration in cancer and is expressed by activated macrophages after brain injury. The function of Gal-3 in the normal brain is unknown, but we serendipitously found that it was expressed by ependymal cells and SVZ astrocytes in uninjured mice. Ependymal cilia establish chemotacti...

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Publication status:
Published

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Publisher copy:
10.1242/jcs.079954

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Journal:
Journal of cell science
Volume:
124
Issue:
Pt 14
Pages:
2438-2447
Publication date:
2011-07-05
DOI:
EISSN:
1477-9137
ISSN:
0021-9533
URN:
uuid:d7c1d63e-305f-4039-bf75-640d579255bb
Source identifiers:
155368
Local pid:
pubs:155368

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