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Journal article

Collagen-induced arthritis in mice.

Abstract:

Collagen-induced arthritis in mice has been widely used to address questions of disease pathogenesis and to validate therapeutic targets for human rheumatoid arthritis. Arthritis is normally observed about 3 wk after immunization with autologous or heterologous type II collagen in complete Freund's adjuvant and susceptibility to the disease is strongly associated with major histocompatibility complex class II genes. The development of collagen-induced arthritis is associated with strong T- an...

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Methods in molecular medicine
Volume:
136
Pages:
191-199
Publication date:
2007
EISSN:
1940-6037
ISSN:
1543-1894
URN:
uuid:d7be6088-005a-4e6d-9328-7ca995451051
Source identifiers:
226607
Local pid:
pubs:226607

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