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Journal article

Identification of key peptide-specific CD4+ T cell responses to human cytomegalovirus: implications for tracking antiviral populations.

Abstract:

Human cytomegalovirus (CMV) infection is normally controlled effectively by the immune response, including CD4(+) T cells. Large numbers of these cells are present in healthy seropositive individuals but their loss in immunosuppression leads to reactivation and disease. Tracking such responses in vivo is hampered by poor definition of their peptide targets. In this study, we defined the key targets of the peptide-specific CD4(+) T cell responses to the CMV pp65 protein using functional assays...

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Publication status:
Published

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Authors


Harcourt, GC More by this author
Scriba, TJ More by this author
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Journal:
Clinical and experimental immunology
Volume:
146
Issue:
2
Pages:
203-210
Publication date:
2006-11-05
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:d7b8988f-2589-4070-ad9f-1ea686a58d93
Source identifiers:
29846
Local pid:
pubs:29846

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