Journal article
Effect of etanercept concentration on human islet integrity
- Abstract:
-
Etanercept is widely used as an antiinflammatory drug to improve engraftment after intraportal islet transplantation. In contrast to other immunosuppressive agents, very little is known about detrimental effects of etanercept on islets. The aim of this pilot study was to define the toxic range of etanercept.Human islets isolated from 8 donors were cultured for 4-5 days at 37°C in culture medium supplemented with etanercept at concentrations from 2.5 to 40 μg/mL, corresponding to potential in ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.transproceed.2017.11.002
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Transplantation Proceedings Journal website
- Volume:
- 49
- Issue:
- 10
- Pages:
- 2327-2329
- Publication date:
- 2017-12-01
- DOI:
- EISSN:
-
1873-2623
- ISSN:
-
0041-1345
- Pmid:
-
29198671
- Source identifiers:
-
811141
Item Description
- Language:
- English
- Pubs id:
-
pubs:811141
- UUID:
-
uuid:d7955c58-338c-4193-83ee-7eb74f13d091
- Local pid:
- pubs:811141
- Deposit date:
- 2018-04-12
Terms of use
- Copyright holder:
- Elsevier Inc
- Copyright date:
- 2017
- Notes:
- © 2017 Elsevier Inc. All rights reserved.
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