Conference item
Lack of effect of ketamine on cortical glutamate and glutamine in healthy volunteers: a proton magnetic resonance spectroscopy study.
- Abstract:
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Ketamine is a N-methyl-D-aspartic acid (NMDA) antagonist that has been associated with temporary clinical improvement in patients with depression. Studies using magnetic resonance spectroscopy (MRS) have shown that major depression is associated with decreased levels of glutamate and glutamine (Glx) in the anterior cingulate cortex, which normalize with clinical recovery. The present study aimed to test whether a ketamine infusion would increase cortical Glx levels in healthy volunteers. Heal...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 868.4KB, Terms of use)
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- Publisher copy:
- 10.1177/0269881111405359
Authors
Bibliographic Details
- Publisher:
- SAGE Publications
- Host title:
- Journal of Psychopharmacology
- Volume:
- 26
- Issue:
- 5
- Pages:
- 733-737
- Publication date:
- 2012-05-01
- Event location:
- United States
- DOI:
- EISSN:
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1461-7285
- ISSN:
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0269-8811
Item Description
- Keywords:
- UUID:
-
uuid:d77f22e0-a9ff-4a14-bc95-266d669f601e
- Local pid:
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pubs:139662
- Source identifiers:
-
139662
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Taylor et al
- Copyright date:
- 2012
- Notes:
- Copyright © The Author(s) 2012. This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm).
- Licence:
- Other
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